Development of Discriminating Method for Dissolution of Aceclofenac Marketed Formulations
نویسندگان
چکیده
منابع مشابه
Assessment of Dissolution Profile of Marketed Aceclofenac Formulations
Statistical comparison of dissolution profiles under a variety of conditions relating to formulation characteristics, lot-to-lot, and brand-to-brand variation attracts interest of pharmaceutical scientist. The objective of this work is to apply several profile comparison approaches to the dissolution data of five-marketed aceclofenac tablet formulations. Model-independent approaches including A...
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Carvedilol (BCS Class II drug) is a nonselective β-adrenergic blocking agent with α1-blocking activity and it is mainly used in the management of hypertension. Two commercial brands of carvedilol drug, of strength 12.5mg were used for the Invitro dissolution studies. In the present study four dissolution media [pH 1.2 (0.1 N Hcl), pH 4.5 Acetate buffer, pH 6.8 phosphate buffer, and Distilled wa...
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In this study five marketed brands of aceclofenac 100 mg tablets have been evaluated using dissolution test in two different media with the aim to assess bioequivalence and to select a proper dissolution medium. Other general quality parameters of these tablets like weight variation, hardness, friability, disintegration time were also determined according to established protocols. All the brand...
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ژورنال
عنوان ژورنال: Dissolution Technologies
سال: 2008
ISSN: 1521-298X
DOI: 10.14227/dt150208p31